Ethyl Acetate → 1,7-Diphenyl-4-heptanol

반응식

[C:1]1([CH2:7][CH2:8][CH2:9][C:10](=[O:20])[CH2:11][CH2:12][CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C(OCC)(=O)C>CCCCCC>[C:14]1([CH2:13][CH2:12][CH2:11][CH:10]([OH:20])[CH2:9][CH2:8][CH2:7][C:1]2[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

실험 절차

Using the procedure of Example 42 with the resultant compound of Example 52 gave, after silica gel chromatography using 15% ethyl acetate in hexane, the desired compound (Rf 0.23, 30% ethyl acetate in hexane) as an oil. 1H NMR (CDCl3) 1.4-1.8 (m, 8H), 2.62 (br t, 4H), 3.63 (m, 1H), 7.15-7.3 (m, 10H). Mass spectrum (M+NH4)+ =286.