Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Ethoxy-2-methyl-6-nitropyridine → 5-Ethoxy-6-methylpyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Ethoxy-2-methyl-6-nitropyridine | HCID 12875016 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 5-Ethoxy-6-methylpyridin-2-amine | HCID 12875017 | 90.8% |
반응 단계
18.2 g of the nitro compound obtained above was suspended in 300 ml of ethanol, which was reduced over 2 g of 5% palladium black under atmospheric pressure. After reaction, the catalyst was filtered off and the solvent was evaporated in vacuo. The residue was crystallized from benzene to obtain 13.8 g of 3-ethoxy-2-methyl-6-aminopyridine (Compound IV where R2 =C2H5), m.p. 98°-99° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04293695 |
| 출처 데이터셋 | uspto-grants-1981_10 |
| ORD ID | ord-7546caff650d435fac3441641d4fbc59 |
| 출처 메모 | uspto-grants-1981_10 |