참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Chloroform | HCID 6212 | — |
| 반응물 | Dimethyl Sulfate | HCID 6497 | — |
| 반응물 | 4-Chloro-2-methoxybenzothiazole | HCID 4141969 | — |
| 생성물 | 4-chloro-N-methylbenzothiazolone | HCID 69645010 | 99.7% |
반응 단계
A mixture of 4-chloro-2-methoxybenzothiazole (3.00 g, 0.015 mole) and dimethyl sulfate (95 mg, 7.5×10-4 mole) was heated at 150° C. for 3 hours with stirring. After cooling, the reaction mass was dissolved in chloroform, and the chloroform layer was washed with an aqueous solution saturated with sodium carbonate and then with water. The solvent was removed under reduced pressure to obtain 2.99 g of 4-chloro-N-methylbenzothiazolone as white crystals. Yield 99.7%, purity 99.0%, m.p. 130°-132° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04293702 |
|---|
| 출처 데이터셋 | uspto-grants-1981_10 |
|---|
| ORD ID | ord-3430b6b0385643a59c87c7ea15694002 |
|---|
| 출처 메모 | uspto-grants-1981_10 |
|---|
