Benzoyl isothiocyanate → N-benzoyl-N'-[3-(2-benzimidazolylamino)propyl]thiourea

반응식

[NH2:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[NH:7][C:8]2[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=2[N:10]=1.[C:15]([N:23]=[C:24]=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:15]([NH:23][C:24]([NH:1][CH2:2][CH2:3][CH2:4][NH:5][C:6]1[NH:10][C:9]2[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=2[N:7]=1)=[S:25])(=[O:22])[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

반응물 2

HCID 68284Benzoyl isothiocyanate

HCID 11593576N1-(1H-benzo[d]imidazol-2-yl)propane-1,3-diamine

생성물 1

HCID 54012460N-benzoyl-N'-[3-(2-benzimidazolylamino)propyl]thiourea

실험 절차

Reacting 2-(3-aminopropylamino)benzimidazole with benzoyl isothiocyanate by the procedure of Example 46 gives N-benzoyl-N'-[3-(2-benzimidazolylamino)propyl]thiourea.

출처 및 근거

ORD 기록: ord-405b4e38ab43443cb983a940ef91848e
출처 데이터셋: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04293697

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