Ethylamine → N-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidine

반응식

[C:1]([NH:3][C:4](=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[CH:16]=[CH:15][S:14][N:13]=1)SC)#[N:2].[NH2:17][CH2:18][CH2:19]SCC1C=CSN=1.C(N)C>>[C:1]([NH:3][C:4]([NH:17][CH2:18][CH3:19])=[N:7][CH2:8][CH2:9][S:10][CH2:11][C:12]1[CH:16]=[CH:15][S:14][N:13]=1)#[N:2]

참가 물질

반응물 3

HCID 6341Ethylamine

HCID 129515372-{[(1,2-Thiazol-3-yl)methyl]sulfanyl}ethan-1-amine

HCID 20567647N-cyano-N'-[2-(3isothiazolylmethylthio)ethyl]-S-methylisothiourea

생성물 1

HCID 54273441N-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidine

실험 절차

Reacting N-cyano-N'-[2-(3-isothiazolylmethylthio)ethyl]-S-methylisothiourea, prepared from 3-[(2-aminoethyl)thiomethyl]isothiazole by the procedure of EXample 3(c) (i), with ethylamine by the procedure of Example 4 gives N-cyano-N'-ethyl-N"-[2-(3-isothiazolylmethylthio)ethyl]guanidine.

출처 및 근거

ORD 기록: ord-ecf8b35219b648b689eda6486728b079
출처 데이터셋: uspto-grants-1981_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04293699

반응 노트

불러오는 중…