Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Acetoxyethyl chloromethyl sulfide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Ethanol, 2-mercapto-, 1-acetate | HCID 98505 | — |
| 반응물 | Calcium Chloride | HCID 5284359 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-Acetoxyethyl chloromethyl sulfide | HCID 12899610 | — |
반응 단계
Hydrogen chloride gas was introduced into a mixture of 2-acetoxyethanethiol (24.0 g) and paraformaldehyde (6.0 g) at a moderate rate with external cooling for 3 hours. Calcium chloride (25 g) was added and the reaction mixture allowed to stand in a salt-ice bath for 4 hours. Methylene chloride (200 ml) was added, the reaction mixture filtered and the solvent evaporated with rigorous exclusion of moisture. The residual oil was distilled to give 2-acetyloxyethyl chloromethyl sulfide (18.5 g, bp 82°-87° C. at 3 mm Hg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04294831 |
| 출처 데이터셋 | uspto-grants-1981_10 |
| ORD ID | ord-fc2246409df24526af69bcb58888db99 |
| 출처 메모 | uspto-grants-1981_10 |