Ammonia → 1-(3-mercapto-1-oxopropyl)-4-oxo-L-proline, methyl ester

HRID 848463노트

반응식

HRID 848463 반응식
C([S:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:17][C:16](=[O:18])[CH2:15][C@H:10]1[C:11]([O:13][CH3:14])=[O:12])=[O:8])(=O)C.N>>[SH:4][CH2:5][CH2:6][C:7]([N:9]1[CH2:17][C:16](=[O:18])[CH2:15][C@H:10]1[C:11]([O:13][CH3:14])=[O:12])=[O:8]

참가 물질

3

반응물 2

HCID 222AmmoniaHCID 127736751-[3-(acetylthio)-1-oxopropyl]-4-oxo-L-proline, methyl ester

생성물 1

HCID 1317125111-(3-mercapto-1-oxopropyl)-4-oxo-L-proline, methyl ester

실험 절차

The product from Example 28 is hydrolyzed with concentrated ammonia according to the procedure of Example 2 to yield 1-(3-mercapto-1-oxopropyl)-4-oxo-L-proline, methyl ester.

출처 및 근거

ORD 기록
ord-63d0e06d22774faeab0eed8cc108d411
출처 데이터셋
uspto-grants-1981_10
특허 번호
US04296113

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