Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methanesulfonic Acid → 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methanesulfonic Acid | HCID 6395 | — |
| 반응물 | 2-Hydroxy-5-(hydroxymethyl)benzaldehyde | HCID 53142 | — |
| 반응물 | Thiobarbituric acid | HCID 2723628 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione | HCID 20564257 | — |
반응 단계
To a solution of 5-hydroxymethyl-salicylaldehyde (5.8 g.) and 2-thiobarbituric acid (6 g.) in n-butanol (100 ml.) add methanesulfonic acid (10 ml.) and heat to reflux, with stirring, for 1 hour. Cool, filter and wash the solid with ethanol and ether to yield 7-n-butyloxymethyl-(1H,3H,5H)-(1)-benzopyrano-(2,3-d)-pyrimidine-4-one-2-thione.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04297355 |
| 출처 데이터셋 | uspto-grants-1981_10 |
| ORD ID | ord-e2191dd56f2446eeb0103dd94f1827d4 |
| 출처 메모 | uspto-grants-1981_10 |