Potassium Carbonate → Methyl 1-[2-(1,3-dioxan-2-yl)ethyl]-2-oxocyclohexanecarboxylate

HRID 849089

반응식

HRID 849089 반응식
[C:1]([CH:5]1[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11])([O:3][CH3:4])=[O:2].Br[CH2:13][CH2:14][CH:15]1[O:20][CH2:19][CH2:18][CH2:17][O:16]1.C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[O:16]1[CH2:17][CH2:18][CH2:19][O:20][CH:15]1[CH2:14][CH2:13][C:5]1([C:1]([O:3][CH3:4])=[O:2])[CH2:10][CH2:9][CH2:8][CH2:7][C:6]1=[O:11]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 170489Cyclohexanecarboxylic acid, 2-oxo-, methyl esterHCID 5206561,3-Dioxane, 2-(2-bromoethyl)-

생성물 1

HCID 18800662Methyl 1-[2-(1,3-dioxan-2-yl)ethyl]-2-oxocyclohexanecarboxylate

시약·촉매·용매 1

HCID 6228Dimethylformamide용매

실험 절차

A solution of 2-carbomethoxycyclohexanone in DMF is reacted with 2-(2-bromoethyl)-1,3-dioxane and potassium carbonate by the method of Example 102 to generate the title compound.

출처 및 근거

ORD 기록
ord-89bcc112ee1949f392bc459e3e029417
출처 데이터셋
uspto-grants-2000_01
특허 번호
US06011028

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