1-Methylpiperidine-2-carboxylic acid → HCID 178480249, 화합물

HRID 849399

반응식

HRID 849399 반응식
[ClH:1].Cl.[NH:3]1[CH:7]=[C:6]([CH2:8][N:9]2[C:15]3[CH:16]=[C:17]([NH2:20])[CH:18]=[CH:19][C:14]=3[CH2:13][N:12]([C:21]([C:23]3[C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[CH:26]=[CH:25][CH:24]=3)=[O:22])[CH2:11][CH2:10]2)[N:5]=[CH:4]1.[CH3:33][N:34]1[CH2:42][CH2:41][CH2:40][CH2:39][CH:35]1[C:36](O)=[O:37]>>[ClH:1].[ClH:1].[ClH:1].[CH3:33][N:34]1[CH2:42][CH2:41][CH2:40][CH2:39][CH:35]1[C:36]([NH:20][C:17]1[CH:18]=[CH:19][C:14]2[CH2:13][N:12]([C:21]([C:23]3[C:32]4[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=4)[CH:26]=[CH:25][CH:24]=3)=[O:22])[CH2:11][CH2:10][N:9]([CH2:8][C:6]3[N:5]=[CH:4][NH:3][CH:7]=3)[C:15]=2[CH:16]=1)=[O:37]

참가 물질

3

반응물 2

HCID 4159391-Methylpiperidine-2-carboxylic acidHCID 1784786502,3,4,5-Tetrahydro-1-(1H-imidazol-4-ylmethyl)-4-(1-naphthalenylcarbonyl)-8-amino-1H-1,4-benzodiazepine, dihydrochloride

생성물 1

HCID 178480249HCID 178480249, 화합물

실험 절차

Example 90 was prepared as a light yellow solid from Example 26 and N-methyl-pipecolic acid as described for Example 62.

출처 및 근거

ORD 기록
ord-f49444eb2ca848139cd310ee650cb8ba
출처 데이터셋
uspto-grants-2000_01
특허 번호
US06011029

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