Potassium Hydroxide → Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

HRID 850334노트

반응식

HRID 850334 반응식
[C:1]([C:5]1[CH:6]=[C:7]([CH2:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].[OH-].[K+]>C1C=CC=CC=1.O.[Fe-3](C#N)(C#N)(C#N)(C#N)(C#N)C#N.[K+].[K+].[K+]>[C:12]([C:9]1[C:10](=[O:11])[C:5]([C:1]([CH3:2])([CH3:3])[CH3:4])=[CH:6][C:7](=[CH:16][C:17]([O:19][CH2:20][CH3:21])=[O:18])[CH:8]=1)([CH3:13])([CH3:14])[CH3:15]

참가 물질

6

반응물 2

HCID 14797Potassium HydroxideHCID 13908126Ethyl (3,5-di-t-butyl-4-hydroxyphenyl)-acetate

생성물 1

HCID 22019852Ethyl (3,5-di-t-butyl-4-oxocyclohexa-2,5-dienylidene)acetate

시약·촉매·용매 3

HCID 178511488HCID 178511488, 화합물촉매HCID 241Benzene용매HCID 962Water용매

반응 조건

온도
40 °C

실험 절차

In benzene (150 mL) was dissolved Intermediate 10 (6.7 g, 22.9 mmol) and this treated with a solution of potassium hydroxide (13.9 g [85%], 210 mmol) and potasium ferricyanide (K3Fe(CN)6) (15.2 g, 46 mmol) in water (150 mL). The mixture stirred under nitrogen atmosphere at 40° C. for 2 hours. The benzene layer then separated, washed with brine (100 mL) and dried over magnesium sulfate. The solvent was evaporated in vacuo to give a red oil, 6.1 g (92%), which was used as is.

후처리

  1. customThe benzene layer then separated
  2. washwashed with brine (100 mL)
  3. dry with materialdried over magnesium sulfate
  4. customThe solvent was evaporated in vacuo
  5. customto give a red oil, 6.1 g (92%), which

출처 및 근거

ORD 기록
ord-4eae0ab84fa34408a0f311abf2920d41
출처 데이터셋
uspto-grants-2000_01
특허 번호
US06017918

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