Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quinoline → Ethyl 3-aminopent-4-enoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quinoline | HCID 7047 | — |
| 반응물 | Ethyl 3-amino-4-pentynoate | HCID 22006121 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Pd barium sulfate | HCID 16218511 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 3-aminopent-4-enoate | HCID 10057602 | 185.1% |
반응 단계
A mixture of 5% Pd/BaSO4 (0.025 g) and quinoline (0.30 mL) was stirred under a ballon of hydrogen for 30 minutes. 3-Amino-pent-4-ynoic acid ethyl ester 17-1 (1.77 g, 10.0 mmol) in EtOH (15 mL) was added and the solution stirred for an additional 2.5 hours. The solution was filtered through a pad of celite and concentrated in vacuo to provide 2.65 g of crude product 19-1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06017926 |
| 출처 데이터셋 | uspto-grants-2000_01 |
| ORD ID | ord-d1d55e3e70e0485588959b6a2941dcb8 |
| 출처 메모 | uspto-grants-2000_01 |