Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hexadecylamine → Methyl 6-hexadecylamino-3-pyridinecarboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hexadecylamine | HCID 8926 | — |
| 반응물 | Hexamethylphosphoramide | HCID 12679 | — |
| 반응물 | Methyl 6-chloropyridine-3-carboxylate | HCID 254249 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | Methyl 6-hexadecylamino-3-pyridinecarboxylate | HCID 20503576 | — |
반응 단계
A mixture of 5.13 g. of methyl 6-chloronicotinate, 7.23 g. of hexadecylamine and 150 ml. of hexamethylphosphoramide is stirred at 130° for 6 hours. Cooling and dilution with water affords a precipitate which is collected by filtration and recrystallized from ethyl acetate and then from acetone to yield methyl 6-hexadecylamino-3-pyridinecarboxylate as a tan solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04382143 |
| 출처 데이터셋 | uspto-grants-1983_05 |
| ORD ID | ord-7f9c119ebae74df0aa104b0070b383ea |
| 출처 메모 | uspto-grants-1983_05 |