Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzimidazole → 2-(2-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)phenyl)-1H-benzo[d]imidazole-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzimidazole | HCID 5798 | — |
| 반응물 | 2,3-Diaminobenzoic acid | HCID 198069 | — |
| 반응물 | Tert-butyl 4-(2-formylphenoxy)piperidine-1-carboxylate | HCID 58279027 | — |
| 생성물 | 2-(2-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)phenyl)-1H-benzo[d]imidazole-4-carboxylic acid | HCID 67203282 | — |
반응 단계
The same general procedure outlined above for the preparation of benzimidazole derivatives was used, employing 2,3-diaminobenzoic acid 1 and tert-butyl 4-(2-formylphenoxy)piperidine-1-carboxylate 26 to produce 2-(2-(1-(tert-butoxycarbonyl)piperidin-4-yloxy)phenyl)-1H-benzo[d]imidazole-4-carboxylic acid 27. MS (ESI) calcd for C24H27N3O5: 437.20; found: 438 [M+H].
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846947B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-eca130390ed14a34a525b6f814aea8f2 |
| 출처 메모 | uspto-grants-2014_09 |