Sulfuric Acid → HCID 20502722, 화합물

HRID 851165노트

반응식

HRID 851165 반응식
[C:1]([C:3]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][CH2:5][CH:4]=1)#N.[H-].C([Al+]CC(C)C)C(C)C.[OH:23]S(O)(=O)=O>C1C=CC=CC=1.C1(C)C=CC=CC=1>[CH:1]([C:3]1[C:8]2[CH:9]=[CH:10][CH:11]=[CH:12][C:7]=2[S:6][CH2:5][CH:4]=1)=[O:23]

참가 물질

6

반응물 3

HCID 1118Sulfuric AcidHCID 132277052H-1-Benzothiopyran-4-carbonitrileHCID 21225700Diisobutylaluminumhydride

생성물 1

HCID 20502722HCID 20502722, 화합물

시약·촉매·용매 2

HCID 241Benzene용매HCID 1140Toluene용매

실험 절차

0.5 g of 4-cyano-2H-1-benzothiopyrane in 2 ml of benzene are reacted with 2 ml of a 20% solution of diisobutylaluminium hydride in toluene and the mixture stirred for 4 hours at room temperature. The resulting mixture is poured onto 20% H2SO4 and the organic phase separated, washed with saturated aqueous NaCl and dried over MgSO4. After concentration by evaporation the product is purified by chromatography over kieselgel (eluant hexane/ethyl acetate).

후처리

  1. customthe organic phase separated
  2. washwashed with saturated aqueous NaCl
  3. dry with materialdried over MgSO4
  4. concentrationAfter concentration
  5. customby evaporation the product
  6. customis purified by chromatography over kieselgel (eluant hexane/ethyl acetate)

출처 및 근거

ORD 기록
ord-2e338e6c31cf4deeba09d532a7e12bd2
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04382951

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