Trimethyl phosphite → Phosphinecarboxylic acid, dimethoxy-, cyclohexyl ester, oxide

HRID 851708

반응식

HRID 851708 반응식
C[O:2][P:3]([O:6][CH3:7])[O:4][CH3:5].[CH:8]1([O:14][C:15](Cl)=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1>>[CH:8]1([O:14][C:15]([P:3](=[O:2])([O:6][CH3:7])[O:4][CH3:5])=[O:16])[CH2:13][CH2:12][CH2:11][CH2:10][CH2:9]1

참가 물질

3

반응물 2

HCID 8472Trimethyl phosphiteHCID 83262Carbonochloridic acid, cyclohexyl ester

생성물 1

HCID 512109Phosphinecarboxylic acid, dimethoxy-, cyclohexyl ester, oxide

실험 절차

From 24.8 g (0.20 mole) of trimethylphosphite and 32.1 g (0.20 mole) of cyclohexylchloroformate. (Y. Iwakura and A. Nabeya, J. Org. Chem. 25 (1960) 1118; M. E. Fourneau et al. Chem. Abstr. 16 (1922) 240; J. H. Saunders et al. J. Am. Chem. Soc. 73 (1951) 3797). (100° C., 2 hours). Yield 30 g (64%). Bp1.4-1.8 148°-151° C. nD21 1.4543.

후처리

  1. custom(100° C., 2 hours)
  2. customBp1.4-1.8 148°-151° C.

출처 및 근거

ORD 기록
ord-d9c6470e7d8542e8a26b078d80e40ed5
출처 데이터셋
uspto-grants-1983_05
특허 번호
US04386081

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