Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sulfuric Acid → Dimedone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sulfuric Acid | HCID 1118 | — |
| 반응물 | 3,3-Dimethyl-5-oxohexanoic acid | HCID 11332610 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | Dimedone | HCID 31358 | 82.3% |
반응 단계
A solution of 5 parts of 5-keto-3,3-dimethylhexanoic acid and about 15 parts of 73% sulfuric acid was heated for one hour in a 130°-135° oil bath. The cooled solution was then poured into a separatory funnel containing ice and chloroform. The aqueous phase was then washed three times with additional chloroform. The combined organic extractions were then dried and evaporated. There was obtained an 82.3% yield of dimedone. It was further recrystallized from toluene.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04386222 |
| 출처 데이터셋 | uspto-grants-1983_05 |
| ORD ID | ord-d7eca5d1c32145dd995fe32b68df792d |
| 출처 메모 | uspto-grants-1983_05 |