2-Ethylbenzimidazole → 2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole

HRID 851845

반응식

[CH2:1]([C:3]1[NH:4][C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2].[CH3:12][O:13][CH2:14][CH2:15][O:16][CH2:17][CH2:18]Cl>>[CH2:1]([C:3]1[N:4]([CH2:18][CH2:17][O:16][CH2:15][CH2:14][O:13][CH3:12])[C:5]2[CH:11]=[CH:10][CH:9]=[CH:8][C:6]=2[N:7]=1)[CH3:2]

참가 물질

반응물 2

HCID 158072-Ethylbenzimidazole

HCID 94934Ethane, 1-(2-chloroethoxy)-2-methoxy-

생성물 1

HCID 44742762-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole수율 77%

실험 절차

2-Ethyl-1-[2-(2-methoxyethoxy)ethyl]-1H-benzimidazole was synthesized as in Synthesis Example 1 except that an equimolar amount of 2-ethylbenzimidazole was used instead of benzimidazole and an equimolar amount of 2-chloroethyl 2-methoxyethyl ether was used instead of 2-chloroethyl methyl ether. Yield 77%.

출처 및 근거

ORD 기록: ord-6f8ac4ad6ece44e596a4f65f55eb6963
출처 데이터셋: uspto-grants-2007_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07252925B2

연결된 노트

불러오는 중…