Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Chloro-alpha-(3-methoxyphenyl)-3-pyridinemethanol → (2-Chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Chloro-alpha-(3-methoxyphenyl)-3-pyridinemethanol | HCID 20145733 | — |
| 촉매 | HCID 178418406 | HCID 178418406 | — |
| 용매 | Toluene | HCID 1140 | — |
| 생성물 | (2-Chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanone | HCID 10243711 | 66% |
반응 단계
Combine (2-chloro-pyridin-3-yl)-(3-methoxy-phenyl)-methanol (9.40 g, 37.6 mmol), manganese (IV) oxide (30.0 g, 0.345 mol) and toluene (500 mL) and heat to reflux for one hour. Filter reaction mixture through celite, wash with toluene:dichloromethane mixture and evaporate to give the title compound (1.63 g, 66% Yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07253165B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-c911483f263244228b471f1f0eb54e62 |
| 출처 메모 | uspto-grants-2007_08 |