Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → (S)-1-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-3-piperidin-1-yl-propan-2-ol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole | HCID 11254641 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | (S)-1-[4-(6-fluoro-benzo[d]isoxazol-3-yl)-phenoxy]-3-piperidin-1-yl-propan-2-ol | HCID 9951259 | — |
반응 단계
The title compound is prepared from a mixture of (S)-6-fluoro-3-(4-oxiranylmethoxy-phenyl)-benzo[d]isoxazole in dimethylformamide and piperidine in ethanol essentially as described above in Example 21. Purity by LC/MS=100%, [M+H]+=371.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07253165B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-61592bdb884b468085c94bab0c9e1736 |
| 출처 메모 | uspto-grants-2007_08 |