3-(Trifluoromethyl)aniline → 2-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine

HRID 852323노트

반응식

HRID 852323 반응식
Cl[C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[F:19][C:20]([F:29])([F:28])C1C=C(C=CC=1)N.N1C=CC=CC=1C=O>>[F:19][C:20]([F:29])([F:28])[C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 3

HCID 73753-(Trifluoromethyl)anilineHCID 142732-PyridinecarboxaldehydeHCID 99213692-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine

생성물 1

HCID 99658212-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine

실험 절차

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3-trifluoromethylaniline (195 mg, 1.2 mmol) and pyridine-2-carboxaldehyde (128 mg, 1.2 mmol) were employed to obtain 2-[2-(3-trifluoromethylphenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.

출처 및 근거

ORD 기록
ord-e512582ce1bd4384847d9c56689bded5
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253190B2

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