2-Pyridinecarboxaldehyde → 2-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridine

HRID 852328노트

반응식

HRID 852328 반응식
Cl[C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1.[F:19]C1C=C(NC2C=CC=CC=2)C=CC=1.N1C=CC=CC=1C=O>>[F:19][C:2]1[CH:3]=[C:4]([N:8]2[N:12]=[N:11][C:10]([C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)=[N:9]2)[CH:5]=[CH:6][CH:7]=1

참가 물질

4

반응물 3

HCID 142732-PyridinecarboxaldehydeHCID 27744663-fluoro-N-phenylanilineHCID 99213692-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine

생성물 1

HCID 691530292-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridine

실험 절차

Following the procedure described in EXAMPLE 1 for the synthesis of 2-[2-(3-chlorophenyl)-2H-tetrazol-5-yl]pyridine, 3-fluorophenylaniline (33.3 mg, 0.3 mmol) and 2-pyridinecarboxaldehyde (32.1 mg, 0.3 mmol) were employed to obtain 2-[2-(3-fluorophenyl)-2H-tetrazol-5-yl]pyridine as an orange solid.

출처 및 근거

ORD 기록
ord-a2b2f27e00d7426b97c919f9a3731bea
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253190B2

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