Benzene, 1-(4-iodo-1-butyn-1-yl)-4-(trifluoromethyl)- → 2-Methyl-2-{2-methyl-4-[4-(4-trifluoromethyl-phenyl)-but-3-ynylsulfanyl]-phenoxy}-propionic acid ethyl ester

HRID 852356노트

반응식

HRID 852356 반응식
[CH2:1]([O:3][C:4](=[O:20])[C:5]([O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][C:16](=O)[CH3:17])=[CH:11][C:10]=1[CH3:19])([CH3:7])[CH3:6])[CH3:2].ICC[C:24]#[C:25][C:26]1[CH:31]=[CH:30][C:29]([C:32]([F:35])([F:34])[F:33])=[CH:28][CH:27]=1>>[CH2:1]([O:3][C:4](=[O:20])[C:5]([CH3:7])([O:8][C:9]1[CH:14]=[CH:13][C:12]([S:15][CH2:16][CH2:17][C:24]#[C:25][C:26]2[CH:31]=[CH:30][C:29]([C:32]([F:33])([F:34])[F:35])=[CH:28][CH:27]=2)=[CH:11][C:10]=1[CH3:19])[CH3:6])[CH3:2]

참가 물질

3

반응물 2

HCID 69458210Benzene, 1-(4-iodo-1-butyn-1-yl)-4-(trifluoromethyl)-HCID 865978202-(4-Acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester

생성물 1

HCID 694603332-Methyl-2-{2-methyl-4-[4-(4-trifluoromethyl-phenyl)-but-3-ynylsulfanyl]-phenoxy}-propionic acid ethyl ester

실험 절차

In analogy to the procedure described in example 1D], 2-(4-acetylsulfanyl-2-methyl-phenoxy)-2-methyl-propionic acid ethyl ester (example 1C]) was reacted with 1-(4-iodo-but-1-ynyl)-4-trifluoromethyl-benzene (example 2E]) to give the title compound as colorless oil.

출처 및 근거

ORD 기록
ord-c2813a27cf19480a9a2be4bc121549da
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253192B2

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