4-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine → 2-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

HRID 852772노트

반응식

HRID 852772 반응식
[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[N+:17]([O-])=O>CO.[Pd]>[CH3:1][C:2]1[CH:16]=[CH:15][C:5]([O:6][CH2:7][CH2:8][N:9]2[CH2:14][CH2:13][O:12][CH2:11][CH2:10]2)=[CH:4][C:3]=1[NH2:17]

참가 물질

4

반응물 1

HCID 589298674-(2-(4-Methyl-3-nitrophenoxy)ethyl)morpholine

생성물 1

HCID 393350392-Methyl-5-[2-(morpholin-4-yl)ethoxy]aniline

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

To the mixture of 4-(2-(4-methyl-3-nitrophenoxy)ethyl)morpholine (532 mg, 2 mmol) in MeOH (50 mL) was added 10% Pd/C (250 mg). The mixture was stirred under an atmosphere of H2 (balloon) overnight. The contents of the reaction mixture were then filtered and concentrated in vacuo to give the title product, which was used without further purification.

후처리

  1. filtrationThe contents of the reaction mixture were then filtered
  2. concentrationconcentrated in vacuo

출처 및 근거

ORD 기록
ord-e895ccfadc854bd78bcc46650cb7ffa5
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253196B2

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