4-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol → 4-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehyde

HRID 85344노트

반응식

HRID 85344 반응식
[CH2:1]([N:5]([CH2:22][CH2:23][CH2:24][CH3:25])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH2:18][OH:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH3:4]>ClCCl.[O-2].[O-2].[Mn+4]>[CH2:22]([N:5]([CH2:1][CH2:2][CH2:3][CH3:4])[C:6]1[CH:11]=[CH:10][C:9]([CH:12]=[CH:13][C:14]2[CH:21]=[CH:20][C:17]([CH:18]=[O:19])=[CH:16][CH:15]=2)=[CH:8][CH:7]=1)[CH2:23][CH2:24][CH3:25]

참가 물질

4

반응물 1

HCID 680087414-[2-[4-(Dibutylamino)phenyl]vinyl]benzyl alcohol

생성물 1

HCID 713628364-{2-[4-(Dibutylamino)phenyl]ethenyl}benzaldehyde수율 64.1%

시약·촉매·용매 2

HCID 178418406HCID 178418406, 화합물촉매HCID 6344Dichloromethane용매2회

실험 절차

In 30 ml of dichloromethane was suspended 6.0 g (69.0 mmol) of active manganese dioxide. Next, 1.17 g (3.45 mmol) of 4-[2-[4-(dibutylamino)phenyl]vinyl]benzyl alcohol was dissolved in dichloromethane and added to the suspension. After stirred at room temperature for 20 hours, the suspension was filtrated and the solvent was evaporated off. The residue was purified by silica gel column, chromatography to give 0.74 g of a yellow crystal (yield: 64.1%).

후처리

  1. additionadded to the suspension
  2. filtrationthe suspension was filtrated
  3. customthe solvent was evaporated off
  4. customThe residue was purified by silica gel column, chromatography

출처 및 근거

ORD 기록
ord-7a2dbfd4835043ee919503c0d17b2a8b
출처 데이터셋
uspto-grants-2014_09
특허 번호
US08846955B2

반응 노트

불러오는 중…