4-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester → 4-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester

HRID 853497노트

반응식

HRID 853497 반응식
[CH3:1][O:2][C:3]([C:5]1[O:23][C:8]2=[N:9][CH:10]=[CH:11][C:12]([O:13][C:14]3[CH:19]=[CH:18][C:17]([N+:20]([O-])=O)=[CH:16][CH:15]=3)=[C:7]2[CH:6]=1)=[O:4]>[Fe]>[CH3:1][O:2][C:3]([C:5]1[O:23][C:8]2=[N:9][CH:10]=[CH:11][C:12]([O:13][C:14]3[CH:19]=[CH:18][C:17]([NH2:20])=[CH:16][CH:15]=3)=[C:7]2[CH:6]=1)=[O:4]

참가 물질

3

반응물 1

HCID 589314974-(4-Nitrophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester

생성물 1

HCID 589314624-(4-Aminophenoxy)furo[2,3-b]pyridine-2-carboxylic acid methyl ester수율 86.9%

시약·촉매·용매 1

HCID 23925Iron촉매

실험 절차

4-(4-Nitrophenoxy)-furo[2.3-b]pyridine-2-carboxylic acid methyl ester (70 mg) was subjected to iron reduction by the same method as in Production Example 10 to obtain the title compound (55 mg).

출처 및 근거

ORD 기록
ord-4d23a21143af4280aa61a0bbf85790e4
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07253286B2

반응 노트

불러오는 중…