Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-(Benzyloxycarbonylamino)propyl 2-acetoxybenzoate → 3-Aminopropyl 2-acetoxybenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-(Benzyloxycarbonylamino)propyl 2-acetoxybenzoate | HCID 59193239 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Aminopropyl 2-acetoxybenzoate | HCID 59193237 | — |
반응 단계
A mixture of 3-(benzyloxycarbonylamino)propyl 2-acetoxybenzoate (2.0 g, 5.4 mmol), 10% Pd/C (0.2 g) and CH3OH (50 mL) was stirred under a H2 atmosphere (RT, 16 h). The mixture was filtered and concentrated under reduced pressure to afford a colorless oil. Purification by silica gel chromatography afforded 3-aminopropyl 2-acetoxybenzoate as a colorless oil. Mass calculated for C12H15NO4=237.25; found: [M+H]+=238.3.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846972B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-e345c465e3cc4d1baf6ce184b46890de |
| 출처 메모 | uspto-grants-2014_09 |