Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Aspirin → 2-Acetoxybenzoyl chloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Aspirin | HCID 2244 | — |
| 반응물 | Oxalyl chloride | HCID 65578 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Acetoxybenzoyl chloride | HCID 79668 | — |
반응 단계
To a solution of compound 2-acetoxybenzoic acid (1.0 g, 5.5 mmol) in THF (30 mL) was added (COCl)2 (0.8 mL, 9.1 mmol) at 0° C. The mixture was heated (reflux, 1.5 h) and concentrated under reduced pressure to afford 2-(chlorocarbonyl)-phenyl acetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08846972B2 |
| 출처 데이터셋 | uspto-grants-2014_09 |
| ORD ID | ord-ffa9aee03798440c969400fefb0bae74 |
| 출처 메모 | uspto-grants-2014_09 |