2,2-Dimethylspiro[5,5]undec-8-en-1-one → HCID 22935662, 화합물

HRID 853741노트

반응식

HRID 853741 반응식
[CH3:1][C:2]1([CH3:14])[CH2:7][CH2:6][CH2:5][C:4]2([CH2:12][CH2:11][CH:10]=[CH:9][CH2:8]2)[C:3]1=[O:13].[CH3:15][Li]>>[CH3:15][C:3]1([OH:13])[C:4]2([CH2:12][CH2:11][CH:10]=[CH:9][CH2:8]2)[CH2:5][CH2:6][CH2:7][C:2]1([CH3:14])[CH3:1]

참가 물질

3

반응물 2

HCID 103525712,2-Dimethylspiro[5,5]undec-8-en-1-oneHCID 178418348HCID 178418348, 화합물

생성물 1

HCID 22935662HCID 22935662, 화합물수율 98%

실험 절차

2,2-Dimethylspiro[5,5]undec-8-en-1-one was treated with methyllithium according to the general procedure (example 2, procedure 5) to give 1,2,2-trimethylspiro[5,5]undec-8-en-1-ol in 98% yield. The crude product was purified by bulb-to-bulb distillation (B.p.=140-150° C./0.032 mbar).

출처 및 근거

ORD 기록
ord-71c0e234b0864c9596773ad487e44cc1
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07256170B2

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