4-(Trifluoromethyl)benzaldehyde → HCID 85331940, 화합물

HRID 853931

반응식

HRID 853931 반응식
[CH3:1][C:2]([C:4]1[CH:9]=[C:8]([O:10][CH2:11][C:12]([F:15])([F:14])[F:13])[CH:7]=[CH:6][C:5]=1[O:16][CH2:17][C:18]([F:21])([F:20])[F:19])=[O:3].[F:22][C:23]([F:33])([F:32])[C:24]1[CH:29]=[CH:28][C:27]([CH:30]=O)=[CH:26][CH:25]=1>>[F:21][C:18]([F:19])([F:20])[CH2:17][O:16][C:5]1[CH:6]=[CH:7][C:8]([O:10][CH2:11][C:12]([F:13])([F:14])[F:15])=[CH:9][C:4]=1[C:2](=[O:3])[CH:1]=[CH:30][C:27]1[CH:26]=[CH:25][C:24]([C:23]([F:22])([F:32])[F:33])=[CH:29][CH:28]=1

참가 물질

3

반응물 2

HCID 679964-(Trifluoromethyl)benzaldehydeHCID 27360731-(2,5-Bis(2,2,2-trifluoroethoxy)phenyl)ethan-1-one

생성물 1

HCID 85331940HCID 85331940, 화합물

실험 절차

The title compound was prepared by heating a mixture of 2,5-bis(2,2,2-trifluoroethoxy)acetophenone (200 mg, 0.633 mmol) and α,α,α-trifluoro-p-tolualdehyde (86 ul, 0.633 mmol) similar to Example 1 and isolated as a yellow solid (60.1 mg, 12.7%). 1H NMR (CDCl3): 7.70 (d, J=15.6 Hz, 1H), 7.67 (q, J=8.6, 14.9 Hz, 4H), 7.55 (d, J=15.6 Hz, 1H), 7.33 (d, J=3.3 Hz, 1H), 7.15 (dd, J=3.3, 9.0 Hz, 1H), 6.95 (d, J=9.0 Hz, 1H), 4.46-4.34 (m, 4H).

후처리

  1. temperatureby heating

출처 및 근거

ORD 기록
ord-14406f3c2819420aa168578609e67669
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07256219B2

연결된 노트

불러오는 중…