Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Quinuclidine, 3-amino-, dihydrochloride → N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-quinolinecarboxamide hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Quinuclidine, 3-amino-, dihydrochloride | HCID 197853 | — |
| 반응물 | Quinoline-7-carboxylic acid | HCID 599475 | — |
| 생성물 | N-(1-Azabicyclo[2.2.2]oct-3-yl)-7-quinolinecarboxamide hydrochloride | HCID 69249623 | 71.1% |
반응 단계
Prepared in analogy to the method for Example 1 starting from 183 mg of quinoline-7-carboxylic acid (Seibert et al. J. Am. Chem. Soc. 1946, 68, 2721) and 200 mg of 3-aminoquinuclidine dihydrochloride. 227 mg (71% yield) of the hydrochloride were obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07256288B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-bbedf97ddd5f47c69194e1f8e9fd459c |
| 출처 메모 | uspto-grants-2007_08 |