Trifluoroacetic acid → HCID 10279731, 화합물

HRID 854359노트

반응식

HRID 854359 반응식
[C:1]([C:5]1[CH:39]=[CH:38][C:8]([C:9]([N:11]2[C@@H:15]([C:16]3[N:17]=[CH:18][S:19][CH:20]=3)[C@@H:14]([C:21]3[CH:26]=[N:25][CH:24]=[CH:23][N:22]=3)[CH2:13][C@@:12]2([CH2:34][CH:35]([CH3:37])[CH3:36])[C:27]([O:29]C(C)(C)C)=[O:28])=[O:10])=[CH:7][C:6]=1[O:40][CH3:41])([CH3:4])([CH3:3])[CH3:2].C(O)(C(F)(F)F)=O>>[C:1]([C:5]1[CH:39]=[CH:38][C:8]([C:9]([N:11]2[C@@H:15]([C:16]3[N:17]=[CH:18][S:19][CH:20]=3)[C@@H:14]([C:21]3[CH:26]=[N:25][CH:24]=[CH:23][N:22]=3)[CH2:13][C@@:12]2([CH2:34][CH:35]([CH3:36])[CH3:37])[C:27]([OH:29])=[O:28])=[O:10])=[CH:7][C:6]=1[O:40][CH3:41])([CH3:3])([CH3:4])[CH3:2]

참가 물질

3

반응물 2

HCID 6422Trifluoroacetic acidHCID 131726558HCID 131726558, 화합물

생성물 1

HCID 10279731HCID 10279731, 화합물

실험 절차

The tert-butyl ester from stage A was deprotected with TFA in a similar manner to that described in Example 1, to afford the title compound as a solid.

출처 및 근거

ORD 기록
ord-000c20d9c87b4458a3358d8b2367c438
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07259163B2

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