Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(R,R)-Hydrobenzoin → Piragliatin
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (R,R)-Hydrobenzoin | HCID 853019 | — |
| 반응물 | 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((S)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide | HCID 58697917 | — |
| 생성물 | Piragliatin | HCID 10432339 | — |
반응 단계
2(R)-(3-Chloro-4-methanesulfonyl-phenyl)-3-((R)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide was prepared in a similar manner as 2(R)-(3-chloro-4-methanesulfonyl-phenyl)-3-((S)-3-oxo-cyclopentyl)-N-pyrazin-2-yl-propionamide (Example 47) starting with (R,R)-hydrobenzoin (Wang, Z.-M.; Sharpless, K. B. J. Org. Chem. 1994, 59, 8302).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07259166B2 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-849465014b514ffbbcd5c0e5468788cb |
| 출처 메모 | uspto-grants-2007_08 |