Cyanuric chloride → HCID 178478357, 화합물

HRID 855661노트

반응식

HRID 855661 반응식
[CH:1]1([C:4]2[CH:5]=[C:6]([NH2:9])[NH:7][N:8]=2)[CH2:3][CH2:2]1.[Cl:10][C:11]1[N:16]=[C:15](Cl)[N:14]=[C:13]([Cl:18])[N:12]=1>C1COCC1>[CH:1]1([C:4]2[CH:5]=[C:6]([NH:9][C:15]3[N:14]=[C:13]([Cl:18])[N:12]=[C:11]([Cl:10])[N:16]=3)[NH:7][N:8]=2)[CH2:3][CH2:2]1

참가 물질

4

반응물 2

HCID 7954Cyanuric chlorideHCID 178507266HCID 178507266, 화합물

생성물 1

HCID 178478357HCID 178478357, 화합물수율 50.4%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매2회

실험 절차

A solution of 5-Cyclopropyl-2H-pyrazol-3-ylamine(334 mg, 2.71 mmol) in 2 ml of THF was added dropwise to a solution of 2,4,6-Trichloro-[1,3,5]triazine (500 mg, 2.71 mmol) in 5 ml of THF at room temperature. After 1 hour, the precipitate was collected to afford 370 mg (50.4% yield) of the desired product.

후처리

  1. customthe precipitate was collected

출처 및 근거

ORD 기록
ord-150c57d21d5b49d19e0aecec07a39ba0
출처 데이터셋
uspto-grants-2007_08
특허 번호
US07262200B2

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