Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | Ethyl 3-oxo-3-(pyridin-3-yl)propanoate | HCID 222197 | — |
| 생성물 | 3-(pyridin-3-yl)-4,5-dihydro-1H-pyrazol-5-one | HCID 12448383 | 50% |
반응 단계
The starting material was prepared using an analogous procedure to that described in Example 9. Ethyl-2-(3-pyridylcarbonyl)acetate (1 g, 5.18 mmol) was treated with hydrazine hydrate (251 μl, 5.2 mmol) to give 3-(3-pyridyl)-4,5-dihydro-1H-pyrazol-5-one (413 mg, 50%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07262201B1 |
| 출처 데이터셋 | uspto-grants-2007_08 |
| ORD ID | ord-e6da0555092e4373938afa6d5a060041 |
| 출처 메모 | uspto-grants-2007_08 |