Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Trimethylsilyl cyanide → alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Trimethylsilyl cyanide | HCID 82115 | — |
| 반응물 | N-(4-difluoromethoxybenzylidene)-4-methylthioaniline | HCID 21862828 | — |
| 생성물 | alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile | HCID 21862794 | — |
반응 단계
Following a procedure similar to that described in Example 1(i), but using 4-difluoromethoxybenzaldehyde and 4-methylthioaniline as starting materials, N-(4-difluoromethoxybenzylidene)-4-methylthioaniline was obtained in a yield of 91%. This aniline compound and trimethylsilyl cyanide were then reacted together in a similar manner to that described in Example 1(ii), to give the title compound as a slightly yellow powder (yield 80%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | USRE039420E1 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-57ad9aa7631f4021aea9c24dc81424f8 |
| 출처 메모 | uspto-grants-2006_12 |