돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 856823생성일: 2026년 10월 25일

Trimethylsilyl cyanide → alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrile

https://huagongshe.com/reaction/856823

반응식

참여 물질

역할이름HCID투입량
반응물Trimethylsilyl cyanideHCID 82115—
반응물N-(4-difluoromethoxybenzylidene)-4-methylthioanilineHCID 21862828—
생성물alpha-(4-Difluoromethoxyphenyl)-alpha-(4-methylthioanilino)acetonitrileHCID 21862794—

반응 단계

Following a procedure similar to that described in Example 1(i), but using 4-difluoromethoxybenzaldehyde and 4-methylthioaniline as starting materials, N-(4-difluoromethoxybenzylidene)-4-methylthioaniline was obtained in a yield of 91%. This aniline compound and trimethylsilyl cyanide were then reacted together in a similar manner to that described in Example 1(ii), to give the title compound as a slightly yellow powder (yield 80%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호USRE039420E1
출처 데이터셋uspto-grants-2006_12
ORD IDord-57ad9aa7631f4021aea9c24dc81424f8
출처 메모uspto-grants-2006_12