Ferrous Chloride → HCID 56945463, 화합물

HRID 857832노트

반응식

HRID 857832 반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1.[Fe:23]([Cl:25])[Cl:24]>C1COCC1>[Fe:23]([Cl:25])[Cl:24].[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=[N:8][C@@H:9]1[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]1[N:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][N:18]=1

참가 물질

4

반응물 2

HCID 24458Ferrous ChlorideHCID 100629331-(pyridin-2-yl)-N-((1R,2R)-2-(((pyridin-2-yl)methylidene)amino)cyclohexyl)methanimine

생성물 1

HCID 56945463HCID 56945463, 화합물

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

In a baked Schlenk tube, 1.0 g (3.4 mmol) of trans-N,N′-bispyridin-2-ylmethylenecyclohexane-1,2-diamine are dissolved in 40 ml of THF and admixed with 431 mg (3.4 mmol) of iron(II) chloride (anhydrous). After 0.5 h, the solution becomes dark blue. After stirring at room temperature for another 2 hours, the solvent is removed under reduced pressure and the residue is stirred with 10 ml of heptane. Filtration through a G3 frit gives the product as a dark blue solid in a yield of 1.41 g (3.36 mmol, 99%).

후처리

  1. customthe solvent is removed under reduced pressure
  2. stirringthe residue is stirred with 10 ml of heptane
  3. filtrationFiltration through a G3 frit

출처 및 근거

ORD 기록
ord-f89c31fc201c4952aada0bfe7c6bcd77
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07148174B2

반응 노트

불러오는 중…