4-Chloro-2,5-dimethoxyaniline → N-(4-chloro-2,5-dimethoxyphenyl)-3-fluoro-4-methoxybenzamide

HRID 858224

반응식

HRID 858224 반응식
[Cl:1][C:2]1[C:8]([O:9][CH3:10])=[CH:7][C:5]([NH2:6])=[C:4]([O:11][CH3:12])[CH:3]=1.[F:13][C:14]1[CH:15]=[C:16]([CH:20]=[CH:21][C:22]=1[O:23][CH3:24])[C:17](O)=[O:18]>>[Cl:1][C:2]1[C:8]([O:9][CH3:10])=[CH:7][C:5]([NH:6][C:17](=[O:18])[C:16]2[CH:20]=[CH:21][C:22]([O:23][CH3:24])=[C:14]([F:13])[CH:15]=2)=[C:4]([O:11][CH3:12])[CH:3]=1

참가 물질

3

반응물 2

HCID 228334-Chloro-2,5-dimethoxyanilineHCID 27334013-Fluoro-4-methoxybenzoic acid

생성물 1

HCID 8409357N-(4-chloro-2,5-dimethoxyphenyl)-3-fluoro-4-methoxybenzamide

실험 절차

The title compound was prepared in substantially the same manner as described in Example 1, step a, from 4-chloro-2,5-dimethoxyaniline, and 3-fluoro-4-methoxybenzoic acid and was obtained as a white solid, m.p. 197–199° C.; MS m/e 340 (M+H)+. Analysis for: C16H15ClFNO4 Calc'd: C, 56.56; H, 4.45; N, 4.12. Found: C, 56.33; H, 4.35; N, 4.05.

후처리

  1. customwas obtained as a white solid, m.p. 197–199° C.

출처 및 근거

ORD 기록
ord-34d77f82e27b4d52a91b7fb158aa4e2b
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07148247B2

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