4-Aminophenethyl alcohol → 2-[4-[(2,6-Dimethyl-3-nitro-4-pyridinyl)amino]phenyl]ethanol

HRID 858420

반응식

HRID 858420 반응식
Cl[C:2]1[CH:7]=[C:6]([CH3:8])[N:5]=[C:4]([CH3:9])[C:3]=1[N+:10]([O-:12])=[O:11].[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=1>>[CH3:9][C:4]1[C:3]([N+:10]([O-:12])=[O:11])=[C:2]([NH:13][C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=2)[CH:7]=[C:6]([CH3:8])[N:5]=1

참가 물질

3

반응물 2

HCID 669044-Aminophenethyl alcoholHCID 107027254-Chloro-2,6-dimethyl-3-nitropyridine

생성물 1

HCID 218761502-[4-[(2,6-Dimethyl-3-nitro-4-pyridinyl)amino]phenyl]ethanol

실험 절차

The title compound was prepared according to the procedure described in step 3 of Example 1 from 4-chloro-2,6-dimethyl-3-nitropyridine (Tanaka, A.; et al. J. Med. Chem., 1999, 41, 4408.) and 4-aminophenylethyl alcohol.

출처 및 근거

ORD 기록
ord-61427ba1b59c474786a2b48fb9c56460
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07148234B2

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