Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methylamine → 2-(4-Bromo-phenyl)-N-methyl-isobutyramide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methylamine | HCID 6329 | — |
| 반응물 | Monoethyl malonate | HCID 70615 | — |
| 반응물 | (R)-4-bromo-alpha-methylbenzylamine | HCID 853000 | — |
| 반응물 | 2-(4-Bromophenyl)-2-methylpropanoic acid | HCID 10933679 | — |
| 생성물 | 2-(4-Bromo-phenyl)-N-methyl-isobutyramide | HCID 58762757 | 84% |
반응 단계
The title compound was prepared as described in Step 1 of Example A(39), where 2-(4-bromophenyl)-2-methyl propionic acid was substituted for ethyl hydrogen malonate and methyl amine was substituted instead of (R)-(+)-1-(4-bromophenyl)ethylamine on that example. Yield 84%.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07148226B2 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-a025f88052e6471dbade514643702c64 |
| 출처 메모 | uspto-grants-2006_12 |