Bromine → 5-Bromo-3,3-dimethylbenzofuran-2(3H)-one

HRID 858591

반응식

HRID 858591 반응식
[CH3:1][C:2]1([CH3:12])[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[O:4][C:3]1=[O:11].[Br:13]Br>C(O)(=O)C>[Br:13][C:8]1[CH:9]=[CH:10][C:5]2[O:4][C:3](=[O:11])[C:2]([CH3:12])([CH3:1])[C:6]=2[CH:7]=1

참가 물질

4

반응물 2

HCID 24408BromineHCID 5956202(3H)-Benzofuranone, 3,3-dimethyl-

생성물 1

HCID 162206345-Bromo-3,3-dimethylbenzofuran-2(3H)-one

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

3,3-Dimethyl-3H-benzofuran-2-one (2.81 g, 17.3 mmol) was added to a solution of Bromine (1.51 mL, 29.5 mmoL) and Acetic acid (35 mL) at room temperature, then stirred overnight. The resulting mixture was stripped of solvent, then distilled under high vacuum. The product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

후처리

  1. distillationdistilled under high vacuum
  2. customThe product fraction (2.08 g, 50%) was collected between 65° C. and 79° C.

출처 및 근거

ORD 기록
ord-d713a1dfac634009a7cc69c2a7c1e159
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07148226B2

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