Nitric Acid → HCID 178468909, 화합물
반응식
[N+:1]([O-])([OH:3])=[O:2].[CH2:5]([O:7][C:8](=[O:16])[C:9]1[CH:14]=[CH:13][CH:12]=[C:11]([NH2:15])[CH:10]=1)[CH3:6].[N:17]#[C:18][NH2:19]>C(O)C>[N:1]([OH:3])=[O:2].[CH2:5]([O:7][C:8]([C:9]1[CH:10]=[C:11]([NH:15][C:18]([NH2:19])=[NH:17])[CH:12]=[CH:13][CH:14]=1)=[O:16])[CH3:6]참가 물질
5
실험 절차
Nitric acid (70%, 6.66 mL) is added to a mixture of 3-amino benzoic acid ethyl ester (17.21 g, 104 mmol) and cyanamide (50% in water, 12.1 mL, 156 mmol) in 50 mL of ethanol. The reaction mixture is heated for 24 hours under reflux. It is then cooled to room temperature and filtered. The solid is washed with water, ether and dried to give 3-ethoxycarbonyl-phenyl-guanidine nitrite as a gray solid; ESI-MS (m/z): 208.1 (M+-HNO3+H).
후처리
- temperatureThe reaction mixture is heated for 24 hours
- temperatureunder reflux
- filtrationfiltered
- washThe solid is washed with water, ether
- customdried
출처 및 근거
- ORD 기록
- ord-4f42fc89c4d24dcf89d4fbaf2853fb0d
- 출처 데이터셋
- uspto-grants-2006_12
- 특허 번호
- US07151096B2
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