Thiophene-3-boronic acid → Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

HRID 859252노트

반응식

HRID 859252 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[S:19]1[CH:23]=[CH:22][C:21](B(O)O)=[CH:20]1>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:21]2[CH:22]=[CH:23][S:19][CH:20]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

참가 물질

3

반응물 2

HCID 581760Thiophene-3-boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

생성물 1

HCID 66865115Tert-butyl 2-nitro-4-thien-3-ylphenylcarbamate

실험 절차

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 3-thiopheneboronic acid according to the general procedure B. Obtained as a yellow solid (326 mg).

출처 및 근거

ORD 기록
ord-ad2e947b7a794560873342e937f3f15a
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07151098B2

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