1-Chloro-2-iodobenzene → (2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

HRID 859277

반응식

HRID 859277 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].B1(B2OC(C)(C)C(C)(C)O2)OC(C)(C)C(C)(C)O1.[Cl:37][C:38]1[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=1I>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:39]2[CH:40]=[CH:41][CH:42]=[CH:43][C:38]=2[Cl:37])=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

참가 물질

4

반응물 3

HCID 119931-Chloro-2-iodobenzeneHCID 2733548Bis(pinacolato)diboraneHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

생성물 1

HCID 69592813(2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester

실험 절차

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1), bis(pinacolato)diboron and 1-chloro-2-iodobenzene according to the general procedure C. Obtained as a yellow oil (886 mg).

출처 및 근거

ORD 기록
ord-32f7db18b091439cad232465ebf9c08f
출처 데이터셋
uspto-grants-2006_12
특허 번호
US07151098B2

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