Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-tert.-Butoxycarbonylamino-3-nitro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert.-butyl ester → 1(2h)-Pyridinecarboxylic acid,4-[3-amino-4-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-3,6-dihydro-,1,1-dimethylethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-tert.-Butoxycarbonylamino-3-nitro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert.-butyl ester | HCID 69592837 | — |
| 촉매 | Azanium ZINC chloride | HCID 5362536 | — |
| 생성물 | 1(2h)-Pyridinecarboxylic acid,4-[3-amino-4-[[(1,1-dimethylethoxy)carbonyl]amino]phenyl]-3,6-dihydro-,1,1-dimethylethyl ester | HCID 69592850 | 31.6% |
반응 단계
Prepared from 4-(4-tert.-butoxycarbonylamino-3-nitro-phenyl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert.-butyl ester (Example E1) (256 mg, 0.61 mmol) by reduction with Zn/NH4Cl according to the general procedure G (method c). Obtained as an orange foam (75 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07151098B2 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-d96a05feb0414ada91ed212dd752a896 |
| 출처 메모 | uspto-grants-2006_12 |