돌아가기
Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 859383생성일: 2026년 10월 27일

3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile → {3-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4'-methoxy-biphenyl-4-yl}-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/859383

반응식

참여 물질

역할이름HCID투입량
반응물3-(2,2-Dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrileHCID 11736337—
반응물Carbamic acid,(3-amino-4'-methoxy[1,1'-biphenyl]-4-yl)-,1,1-dimethylethyl esterHCID 69592815—
생성물{3-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4'-methoxy-biphenyl-4-yl}-carbamic acid tert.-butyl esterHCID 86587991—

반응 단계

Prepared from (3-amino-4′-methoxy-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example G5) and 3-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-benzonitrile (Example J4) according to the general procedure K. Obtained as a light brown solid (207 mg).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07151098B2
출처 데이터셋uspto-grants-2006_12
ORD IDord-c855000f534b4ef1a641ec9fcdf8fd8f
출처 메모uspto-grants-2006_12