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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 859415생성일: 2026년 10월 25일

2,2-Dimethyl-6-(3-[1,2,4]triazol-1-yl-phenyl)-[1,3]dioxin-4-one → {4-(4-Fluoro-phenylethynyl)-2-[3-oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/859415

반응식

참여 물질

역할이름HCID투입량
반응물2,2-Dimethyl-6-(3-[1,2,4]triazol-1-yl-phenyl)-[1,3]dioxin-4-oneHCID 22224837—
반응물[2-Amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert-butyl esterHCID 69486641—
생성물{4-(4-Fluoro-phenylethynyl)-2-[3-oxo-3-(3-[1,2,4]triazol-1-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert.-butyl esterHCID 86588023—

반응 단계

Prepared from [2-amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert.-butyl ester (Example G33) and 2,2-dimethyl-6-(3-[1,2,4]triazol-1-yl-phenyl)-[1,3]dioxin-4-one (Example J13) according to the general procedure K. Obtained as a yellow solid (230 mg).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07151098B2
출처 데이터셋uspto-grants-2006_12
ORD IDord-fafcd0f20f87483aac43a2f343e50359
출처 메모uspto-grants-2006_12