Estradiol → (-)-Menthol

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[CH3:1][C@@:2]12[C@@H](O)CC[C@H:15]1[C@H:14]1[C@@H:5]([C:6]3[CH:7]=CC(O)=C[C:11]=3CC1)[CH2:4][CH2:3]2.CC(O[C@]1(C#C)[C@@]2(C)CC[C@@H]3[C@@H]4C(=CC(CC4)=O)CC[C@H]3[C@@H]2CC1)=[O:23]>>[CH3:1][C@H:2]1[CH2:15][C@@H:14]([OH:23])[C@H:5]([CH:6]([CH3:7])[CH3:11])[CH2:4][CH2:3]1

참가 물질

반응물 2

HCID 5757Estradiol

HCID 5832Norethisterone Acetate

생성물 1

HCID 16666(-)-Menthol

실험 절차

The manufacturing method mentioned above was carried out according to this formulation followed by cutting into a desired size to give a mixed preparation of estradiol and norethisterone acetate.

후처리

customto give

출처 및 근거

ORD 기록: ord-e1b077d349bb464ebb4f6bf71fed81c2
출처 데이터셋: uspto-grants-2006_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07153522B1

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