반응식
[Cl:1][C:2]1[CH:3]=[C:4]([CH:6]=[C:7]([Cl:9])[CH:8]=1)[NH2:5].[C:10]([O:15][CH2:16][CH:17]([CH3:19])[CH3:18])(=[O:14])[C:11]([CH3:13])=O>>[CH2:16]([O:15][C:10](=[O:14])[C@H:11]([CH3:13])[NH:5][C:4]1[CH:3]=[C:2]([Cl:1])[CH:8]=[C:7]([Cl:9])[CH:6]=1)[CH:17]([CH3:19])[CH3:18]참가 물질
3
실험 절차
Following General Procedure AA above and using 3,5-dichloroaniline (Aldrich) and iso-butyl pyruvate (prepared by following General Procedure AO above), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
후처리
- customThe reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification
출처 및 근거
- ORD 기록
- ord-0c6be54c185c40c9b9b53cbf0a92453f
- 출처 데이터셋
- uspto-grants-2006_12
- 특허 번호
- US07153847B2
연결된 노트
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