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llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
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3-(4-Azidomethyl-2-methyl-phenyl)-propionic Acid Methyl Ester → 3-(4-Aminomethyl-2-methyl-phenyl)-propionic Acid Methyl Ester

HRID 860653
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인쇄 미리보기

반응식

HRID 860653 반응식
[CH3:1][O:2][C:3](=[O:17])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][N:13]=[N+]=[N-])=[CH:8][C:7]=1[CH3:16].[H][H]>CCO.[Pd]>[CH3:1][O:2][C:3](=[O:17])[CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][C:9]([CH2:12][NH2:13])=[CH:8][C:7]=1[CH3:16]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

5

반응물 2

HCID 574319823-(4-Azidomethyl-2-methyl-phenyl)-propionic Acid Methyl EsterHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 574319803-(4-Aminomethyl-2-methyl-phenyl)-propionic Acid Methyl Ester수율 78.5%

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 702Ethanol용매

실험 절차

A mixture of 3-(4-Azidomethyl-2-methyl-phenyl)-propionic acid methyl ester (0.20 g, 0.86 mmol) and 5% Pd/C (32 mg) in EtOH (50 mL) is exposed to a hydrogen atmosphere (60 psi) at RT overnight. Upon filtering the mixture through Celite, the filtrate is concentrated to yield the title compound (0.14 g, 78%). The material is used without further purification.

후처리

  1. filtrationUpon filtering the mixture through Celite
  2. concentrationthe filtrate is concentrated

출처 및 근거

ORD 기록
ord-e318e750be344ba3b4926b8dbec0027e
출처 데이터셋
uspto-grants-2006_12
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07153878B2

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